I've tried the low method, then cranking them up to 350. The problem I had with that method is, to prevent them from drying out, you can't really get as much smoke on them as I'd like. You seem to have to end the low temp smoking time period too soon.
I also tried the low smoke method until almost completely done, then transfer to my grill at high temps. That definitely works better, IMO. But then the process gets a bit more complicated.
I recently tried the baking powder method, and liked it quite a bit! It allows maximum time at low temps, thus more smoke flavor.