Injecting is probably a great idea, baste occasionally, then probably wrap toward the end to retain moisture. The term "buffalo" however is a misnomer. Buffalo are indigenous to Africa and Asia (water buffalo, cape buffalo, etc). What is available here is Bison, typically what is designated as North American Bison. The differences are the beard on North American, the hump, and the ability to withstand extreme cold. If you took a Cape Buffalo and put it in the plains out west in the Winter, it'd never survive. I learned all of this not too long ago when I bought a bunch of "buffalo" meat for a big shindig we were hosting and the good folks here set me in the direction of learning the difference between the two.
Shedding some light,
Robert