You can safely cook meat at a lower temperature... Below is a "Time / Temperature" guide to safely kill pathogens... It's the same practice used in "Sous Vide".... Holding a piece of meat at a lower temperature, for a longer period of time, has the same effect on pathogens as a high temp for a short period of time..... As far as I know, this chart does not reflect killing botulism, sooooo, do not add smoke using this table... have the dampers wide open for good air flow so there is not an oxygen deficit.... botulism grows in an oxygen deficient atmosphere...
Translation of the number below......
Holding the meat "internal temperature" at a temperature of 135 deg. F., for 36 minutes..... gives the same results as holding the "Internal Temperature" at 158 deg. F., for zero seconds... That makes it safe to eat.... HOWEVER, it may not be dry, or due to a thermometer that is not calibrated correctly, I recommend holding at lower temps for longer periods than the chart shows....
Hope all this makes sense..... Dave
Temperature Time Temperature Time
°F (°C) (Minutes) °F (°C) (Seconds)
130 (54.4) 112 min 146 (63.3) 169 sec
131 (55.0) 89 min 147 (63.9) 134 sec
132 (55.6) 71 min 148 (64.4) 107 sec
133 (56.1) 56 min 149 (65.0) 85 sec
134 (56.7) 45 min 150 (65.6) 67 sec
135 (57.2) 36 min 151 (66.1) 54 sec
136 (57.8) 28 min 152 (66.7) 43 sec
137 (58.4) 23 min 153 (67.2) 34 sec
138 (58.9) 18 min 154 (67.8) 27 sec
139 (59.5) 15 min 155 (68.3) 22 sec
140 (60.0) 12 min 156 (68.9) 17 sec
141 (60.6) 9 min 157 (69.4) 14 sec
142 (61.1) 8 min 158 (70.0) 0 sec
143 (61.7) 6 min
144 (62.2) 5 min
145 (62.8) 4 min
Table C.1: Pasteurization times for beef, corned beef, lamb, pork and cured pork (FDA, 2009, 3-401.11.B.2).