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I spritz with apple juice and sometimes Makers Mark but mostly with apple juice only. IMO it does slightly help with moisture and leaves a sweeter bark. I also use mustard on Butts for bark.
I don't spritz... Its on there for the duration untouched and un-looked-at (is that a word - I think not lol). The only thing I open the lid for is to do a quick meat temp check, and I don't bother checking for the first 75% of estimated cook time.
I have spritz'd in the past and have not found that it made much of a difference, and I prefer a thick, chewy bark anyway.
lol You're right about spritzing. Sounds like something a woman does when she's "not feeling fresh". Actually I've been "spraying" my butt with apple juice and rum. I guess thats a bit more manly. Right?