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All of the above is good advice. We eat a LOT of venison, and I usually don't smoke it unless it is wrapped in bacon.
I have only cured & smoked venison aka pastrami or similar to Canadian bacon. Without a cure my guess would be you should lard or marinate, smoke at higher temps. and pull at about 130 degrees and let rest like a roast in the home oven.
Also you may get more replies if you post this in the game thread.