I pretty much let the fire decide, using wood and charcoal, I opt for ~225, but sometimes the fire has other plans, I haven't done a real study on the exact ways to prepare the fire, eg, newspaper/no newspaper, use charcoal column or not, all wood, start with wood..add charcoal later to steady the temps, start with charcoal and slowly migrate over to wood, or using all charcoal. wood sizes, timing for adding more charcoal all can make a big difference in temps. I pretty much get somewhere where I get a steady temperature range and got with that.
like Mdboatbum, I've done the 17 hour pork shoulder and the 7 hour pork shoulder...I'd prefer the 7 hour smoke.
I'm not one of those guys that smokes at 325 for 3.5 hours, baste, smoke at 250 for 6.25 hours, baste, (add more details and temp changes), foil and park until temps are reached, causes too much stress, although I don't get consistency, I'm only feeding myself, family and friends. and I do get great Q.
my advice would be to relax and go with the flow.