Sanotize....Covid Nasal spray

[JCAP]

Alright I'mma put on my Immunology PhD hat for a bit and say..

This study doesn't tell me squat about efficacy. I have no idea about their Q-PCR methods, they don't report any raw data, there are no CT values reported, they talk nothing about characteristics of the randomization, etc. More of the placebo group had fevers too, so one automatically wonders if the people in the placebo group actually were sicker than those in the NONS group. I also don't know about symptoms of patients while on or after the NONS spray. Did it reduce symptoms too or just bits of RNA in the nose/throat? They say in the discussion that symptoms disappeared faster, but if that's a real finding, why wasn't it reported in the results with data? Probably because it was like improvement by like 2 hours or something. Finally there was also a paper last summer that showed almost everyone who had a virus RNA concentration less than 6 (Log10 RNA) were not infectious. In other words, didn't transmit. Of course that paper used culturable virus and this one just reports RNA bits.


If this actually works, that would be great. But need to see TONS more data.

As of now, it's a one figure sales pitch.

 

[PolishDeli]

Dr JCAP
The study I provided a link to was a peer reviewed research paper. Research is very different than a clinical trial.

Before NONS move to market, they must pass clinical trials. Those are currently underway in several countries, and are designed to answer the excellent question you asked.

WaterRat
NOS = Nitrous Oxide = N2O
The nasal spray in question contains Nitric oxide = NO

 

[WaterRat]

[QUOTE="PolishDeli, post: 2253101, member: 04844]@WaterRat[/USER]
NOS = Nitrous Oxide = N2O
The nasal spray in question contains Nitric oxide = NO
[/QUOTE]
Whoops, You are correct. Even more reason to not to try it at home!

 

[JCAP]

Dr JCAP JCAP
The study I provided a link to was a peer reviewed research paper. Research is very different than a clinical trial.

Wooooo baby! The paper in question reports data from a clinical experiment. Maybe not a full fledged clinical trial registered with a government body, but clinical data nonetheless. It’s more than just a research paper and I think things like this need to be substantiated with rigorous high quality data of which this is absolutely not.

 

[jcam222]

Wooooo baby! The paper in question reports data from a clinical experiment. Maybe not a full fledged clinical trial registered with a government body, but clinical data nonetheless. It’s more than just a research paper and I think things like this need to be substantiated with rigorous high quality data of which this is absolutely not.

Certainly the public data is limited but I’d assume that is fairly normal at this stage in the development?

 

[WaterRat]

Certainly the public data is limited but I’d assume that is fairly normal at this stage in the development?

That's correct.

 

[Smoke-Chem BBQ]

[QUOTE="PolishDeli, post: 2253101, member: 04844]@WaterRat[/USER]
NOS = Nitrous Oxide = N2O
The nasal spray in question contains Nitric oxide = NO

Whoops, You are correct. Even more reason to not to try it at home!
[/QUOTE]

Excellent point. Nitric oxide is very toxic, and can pose a significant inhalation risk...which isn't to say it doesn't have medical uses and a delivery system can't be engineered to deliver a safe inhaled dose, but that isn't trivial. It's not something you could whip up in your kitchen or shop.

Nitric oxide is kinda like selenium or chromium; generally recognized as nasty toxins, yet the body requires just the right amount of them to function.

 

[forktender]

I dont think Racing NOS is meant for Human consumption, but you can get all the food safe WHIPETTES you want at Restaurant and Baking Supply Stores! Head Shops still sell the dispensers to fill Balloons. Damn, that's some late 70's memories....JJ

Wah, wah,wah,wah,wah,wah. They used to sell balloons full of N.O. at concerts back in the 80's.