I usually inject mine 10 - 12 hours before smoking. Keeps them very moist.
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J, morning and welcome to the forum.... good advice on the brine....I've only been at this for a couple of years, so I'm relatively new at this. But just as an fyi for those who've never tried brining a brisket, it's a lot of work, but makes a big difference in the finished product. I make a brine of 1-2 cups of kosher salt, 2 tbsp of whole black peppercorns, 2 tbsp of minced garlic, & 1 whole onion (quarters and separated). I brine the brisket for 6 to 8 hours, depending on size, and then pat dry and use a good rub. Let the meat set with the rub for at least 4 hours until ready to smoke.
The most noticeable difference you'll notice isn't the element of salt or flavor in the meat. That's actually pretty subtle. The biggest difference you'll notice is that the salt acts as a tenderizer. I've been pretty fortunate to have been offered a lot of great advice and so my briskets have always come out very well. But this is one tip I would recommend everyone try at least once. Again, it's a lot of work, but well worth the effort in my opinion. If you don't like it, no harm, no foul. Best of luck!!
I brine when making a smoked pastrami. =. beefI never give a though to brining any cut of beef, maybe a marinade.
I use one herb and the is spice, to make a good new york style ... 3 days for the point and 5 for the flatI brine my briskets, inject with butter, smoke for about ten hours and finish with a Texas choke in a braise pan. Once they hit 205 leave them in the braise pan and gradually bring the temp down to about 160. They come out beefy, juicy and tender. Don't know if they would if I didn't do all that, but I figure why mess with success. Brining won't give you corn beef. You have to add curing salts for that.