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I think 190°-200° is about as low as I would want to cook at unless cold smoking. It has been my experience so far that much below 215° really increases my smoke times. I have tried a couple briskets below 225° like this and didn't think it was really worth the added time it took to finish them.
I think your main concerns at lower temps would be time and letting your meat hang out in the danger zone (40°-140°) too long. Just out of curiousity, why do you ask?
We just got a Klose with the smoker box runnig the main chamber at 250 the smoker box is at 150 and from what I have been told the smoker box cook outstanding chicken I"ll it at 300-325 that should get me at 200-225 We will see thanks for the info Ed