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It really doesn't matter. Some guys let the smoker get to temp, most smoke around 225, then put the meat on. I like to put whatever I'm smoking on when I start the smoker up. That way whatever I am smoking goes thru a small period of cold smoking, while the smoker comes up to temp. The meat or fattie will absorb more smoke when it's cold than it will when it heats up. It's just a personal preference. Either way will work fine.