My jam is 2x through my largest plate, and that's mainly for fat distribution. I don't cube my meat and feed it in long strips when I do it this way. Works good for burgers (leaving some texture), meatloaf, ground meat "casserole style dishes" etc... and if I make breakfast sausage. Grind once, mix in seasoning, grind again to incorporate.
Only time I deviate, 1x though my finest plate. I don't do the fine plate often, but it works good if I want a fine texture, works good for burgers and chili/spaghetti sauce etc. I don't do a lot of chili or spaghetti so my fine plate really is rarely used. I generally cube for this method so I get fat distribution on a single pass, feeding the fattier and leaner in a kind of evenly distributed cubes.
It feels like I actually save time on double grinding since I use long strips and just let the machine gobble it up. My typical batch is 5-6 lbs.