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Ideally, no matter how well-done you've cooked your meat, you want to allow it to cool down until the very center has reached 120°F (49°C). At this stage, the muscle fibers have relaxed enough that you should have no problem with losing juices. As shown in the graph, In a 1.5-inch-thick steak, this translates to around 10 minutes. For a prime rib, this may take as long as 45 minutes.
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