Absolutely
When brisket was .99/lb (and it was that price for a looongg time) I used brisket for about everything. Smoked it, ground it for all of my ground beef, made stews, pot roasts, even jerky out of it.
I clearance shop. Any cut of beef in the meat counter under 3.99/lb I buy. Chuck roast goes on sale for 3.99 or less, I buy a ton. Top round often goes on sale for 2.99/lb, I buy some of them too. When I need grind, all of that clearance meat, some fattier chucks (to make up for the leaner round) and the rounds all go through the grinder. I will have to do some soon, only one pack left.
I would do it if comercial ground beef was 10 cents a lb and every other cut was 5 bucks a lb. Once you start eating home grind, you can't eat store bought anymore. It smells and tastes horrible.