I've smoked many items, but the 22lb turkey I have just smoked may have been the best. Here's how I did it....
Defrost a 20+lb frozen turkey in the fridge for 5 days
Dissolve 1 cup Kosher Salt, 3/4 brown sugar,1 gallon of water, and 1/2 cup of your favorite rub, and then brine the bird for 12-24 hours
Split the bird in half, spatchcock, as it will not cook otherwise. Creating two, 10lb+ halves
Rub the bird with your favorite rub, heavily
Smoke with your favorite wood. I used a mix of Apple and Hickory
4.5 hours on 250 degrees will do it!