OK, been wait'en for tis one, you would be shocked at how many big comp teams rub meat with vinagar, wait 5 minutes and rub with spices and have great success.
Think about it , vinagar will open the pours of meat, more penatration into meat with your faverite rub.
I caught on to this many years ago and ALWAYS rub with vinagar prior to rubbing with spices, and have never had a problem and may be the reson i don,t let the rub set on meat more than 20 min. before putting on the smoker
Also may be suprized at how many commercial rubs have powdered vinager in them.
Just my opinion.