I have to disagree. I am pretty sure If your product will be warmer than 40F (during smoking), Cure #1 is necessary for food safety purposes. The exception being if your product is fully cooked to it's required minimum internal temperature (depending on the meat being used) within 4 hours. Contrary to what a previous poster mentioned, your IT should be higher than 140F. (An IT above the high limit of the "danger zone" does not constitute what is considered to be fully cooked.