some will disagree, some will note a differnce and some will have no clue. when making fresh salsa's, dips and sauce using fresh peppers.most folks will not deseed the peppers but will incorperate them into the dips,salsa and sauces. works great and i sometime do it also. but when I use roasted chiles (peppers) I always take the seeds out and discard them. and more importantly when useing dried chiles (peppers) I always take the seeds out. I find the dried and sometimes the roasted chilis (peppers) seeds have a bitter taste are a nasty taste that makes what ever I am cooking not as great tasting as if the seeds were removed. also the skin of the chilis (peppers) can influence this bitter taste. hence the roasting of the fruit and removing the skins. any of you pepper heads thoughts are welcome... if the pepper is so hot the taste is not as prevelent, but the after taste is still there. trying to make the best..