Yes. I have spatched a turkey. It turned out great.
I went with a high heat >300* over direct coals (put my bird on the top rack of my vertical smoker so it ended up being about 2+ feet above the coals).
Air dry the skin
Cook (took me just over 2 hours)
The main thing with turkey (and most all meat) is to use a probe thermometer. I want to say the internal temp was in the 160* range when I pulled it.