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I'm a relative newbie as well with regards to smoking on an MES. So far I've done 4 Boston butts and they have all turned out great. (thanks to the help on these boards)
Noboundaries is spot on recommending that thread, great info right there.
Figure on about 2 hours per lb at around 225 degrees. I foiled once and have not foiled the last three times. I prefer a bit more bark on my PP.
Have fun, pork is pretty forgiving, try not to drink too much as it is a long cook!