Howdy Paul. Yes, there are many ways to smoke on a Kettle. By asking what is best you'll get techniques people have used successfully. Here's mine.
I have a Smokenator in my Kettle, a $70 "heat fence" that is really just a bent piece of metal but it does work great. What it does is direct all the heat vertically instead of letting some of it radiate horizontally. You get nice air circulation with it and can control your temps with the top vent. It takes a little trial and error to control your temps but you can get quite good at it. You can smoke like the pros with it. A hinged cooking grate is a necessity with either the Smokenator or a firebrick setup. Hinged grates are like $15. I took the hinged section completely off mine so I could more easily access the space when I needed to recharge the fuel.
You can make your own Smokenator type setup much cheaper though by buying a couple firebricks from HD or Lowes to use as a heat fence. Lay them next to each other longwise on the charcoal grate standing up on one edge over toward one side of your kettle. You can use the little half-moon charcoal baskets or just put cold charcoal and wood chunks on the charcoal grate, filling it up about half way. Add 15 or so hot briquettes to the top of the cold pile.
Below is a picture of my Smokenator in my 22.5". Just replace the long side with firebricks and you're good to go. Put the vent on the lid opposite the fire to maximize circulation. If using a One Touch, leave your bottom vent fully open. If using a three vent bottom, close the vent on the bottom opposite the fire.